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Transforming Healthcare with Operator-Led MedTech Investments

Operator-Led MedTech Venture Capital

We partner with visionary entrepreneurs to scale next-gen MedTech globally, solving critical health inefficiencies. Our team brings decades of hands-on experience as founders and operators to not only fund but actively guide companies toward market leadership and successful strategic exits.

One Six 8 Ventures backs entrepreneurs in the early-stage MedTech sector, focusing on high-growth areas including AI-MedTech, surgical tools and robotics, and remote patient monitoring. Our investment approach targets companies in underventured regions, allowing us to identify unique opportunities that others overlook. We provide strategic guidance and connect portfolio companies to large strategic partners, helping them achieve global scale

The Canadian MedTech Opportunity

The Canadian MedTech market presents a compelling opportunity to generate significant returns by funding companies with global impact. Canadian MedTech remains underfunded, creating a favourable investment climate and access to exceptional assets at attractive valuations. This represents an opportune time to focus on MedTech given the urgent global demand driven by aging populations and strained healthcare systems.

Technology has now matured for mass adoption, particularly in areas like artificial intelligence, robotics, and smart diagnostics. Major strategic acquirers actively pursue innovative technologies to expand their portfolios and address evolving market needs. Consolidation continues across the sector, with acquirers targeting companies that offer advanced digital capabilities, differentiated products, and scalable platforms. This trend appears especially evident in robotics, diagnostics, and connected care.

From An Operator's Perspective

Our team comprises seasoned operators and executives with deep experience in scaling MedTech and life science companies backed by venture capital. With nearly two decades in the industry, we bring hands-on operational leadership and disciplined financial stewardship from C-suite roles.

This allows us to actively partner with portfolio companies post-investment, providing strategic guidance and operational support that proves fundamental to navigating challenges, preserving capital, and accelerating growth toward market leadership.

We understand the journey because we've walked it ourselves. Our expertise extends beyond capital allocation to encompass the strategic and operational realities of building successful MedTech companies in today's competitive landscape.

In the Media

  • PulseMedica won the health.tech startup competition in Basel for its platform designed to image and treat eye floaters.

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  • Respiree partnered with Philips to integrate wearable sensors and predictive AI into the Philips monitoring ecosystem.

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  • ThinkSono received an FDA breakthrough designation for its AI algorithm designed to detect deep vein thrombosis.

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  • Forbes featured Managing Partner Judyanna Yu for her insights on the growth of MedTech as a promising venture capital frontier.

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  • Invest In Her Podcast host Catherine Gray interviewed Judyanna Yu on life sciences and transformative medical technologies.

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  • Fluid Biomed secured $27 million USD in Series A financing to advance the first bioabsorbable polymer-based stent for brain aneurysms.

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  • ThinkSono obtained EU approval for the first ultrasound AI software designed for blood clot assessment.

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  • Digital Journal explored how strategic investment can help Canadian MedTech companies expand into global markets.

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  • ThinkSono FDA Clearance

    Shortly after One Six 8 Ventures’ investment, ThinkSono received FDA clearance for ThinkSono Guidance, marking an important milestone in its US expansion.

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Testimonials

  • "One Six 8 has been a tremendous partner for Tenomix. From early on, their team really took the time to understand our business, the market we’re building in, and the long-term potential of our platform. Their diligence questions were thoughtful and showed real med-tech experience, but what stood out most was how quickly they went to bat for us - connecting us with strategics in our space, sector experts, and important stakeholders across their global network. My team and I are really excited to work with the One Six 8 team as we enter this next chapter of growth at Tenomix”.

    —Saumik Biswas, Ph.D., CEO, President and Founder, Tenomix

  • “Working with One Six 8 Ventures has been a real pleasure from start to finish. They’re a rare breed of investor that is both very diligent, but also fast at assessing opportunities. Within a span of a few months after they invested, they made strategic introductions to ThinkSono that has already been extremely helpful. I can’t recommend them enough”

    —Fouad Al-Noor, CEO & Co-Founder, ThinkSono

  • "Working with One Six 8 Ventures has been a great experience. They understand our vision, back us for the long term, and open doors that help us grow."

    —Gurpreet Singh, Ph.D., MBA, CEO and Founder, Respiree

Building the Future Together

View our portfolio to see the innovative companies we're supporting, or connect with our team to explore partnership opportunities.